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A cholera outbreak has occurred, and the culprit is contaminated drinking water. Which controllable risk factors might have caused this outbreak? Check all that apply.

The unsanitary handling of human waste by nearby waterways.
The genetic makeup of individuals reporting cholera-related symptoms.
The significant difference in reported cases between males and females.
The reduction in accessibility to regions that use filtered bottled water.
The lack of access individuals with symptoms have to health clinics.