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The chemical colchicine is used in the production of karyotypes. Colchicine prevents spindle fibers from forming during the cell cycle. What is a result of preventing spindle fibers from forming? Answer
A The cell cycle skips G1 phase
B Mitotic division is skipped, and the cell cycle proceeds to cytokinesis.
C Mitotic division stops in metaphase and cannot proceed to anaphase.
D The cell cycle skips S phase and proceeds to G2 phase.​

Sagot :

Answer: the correct answer is C

Explanation:

Preventing the formation of spindle fibers makes the mitotic division stop in metaphase, and thus fail to proceed to anaphase.  

• Colchicine prevents the polymerization of the microtubule, and thus, prevents the arrangement of the mitotic spindle, which shows the prevalence of another checkpoint in the cell cycle.  

• As a result, the activity of the maturation promoting factor remains high, the chromosomes stay condensed, and the nuclear envelope fails to redevelop.  

• A toxic effect is exerted on the living cells by the colchicine, which usually results in the arrest of the process of mitosis at an eventual stage, generally the metaphase, with the generation of unusual and bizarre nuclear configurations, and thus, resulting in the death of the cell.

Thus, the correct answer is option C.

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