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what is the effect of the abnormal protein on tissue function in duchenne muscular dystrophy and skeletal muscle tissue?

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Answer:

Lack of the dystrophin protein in muscle cells causes them to be fragile and easily damaged. DMD carriers are females who have a normal dystrophin gene on one X chromosome and an abnormal dystrophin gene on the other X chromosome. Most carriers of DMD do not themselves have signs and symptoms of the disease, but a minority do. Symptoms can range from mild skeletal muscle weakness or cardiac involvement to severe weakness or cardiac effects and can begin in childhood or adulthood.

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