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Sagot :
Answer:
The correct option is - (a) the activation and inactivation gates must both be open.
Explanation:
Option (a) is correct because of the following reason -
The axonal membrane is at its natural resting potential until an action potential occurs, and [tex]Na^+[/tex] channels are deactivated and blocked on the extracellular side by their activation gates. The activation gates open in response to an electric current, allowing positively charged [tex]Na^+[/tex] ions to flow into the neuron through the channels. When enough [tex]Na^+[/tex] has penetrated the neuron and the membrane potential has reached a certain level, the [tex]Na^+[/tex] channels inactivate themselves by closing their inactivation gates at the height of the action potential. The inactivation gate can be thought of as a "plug" tethered to the intracellular alpha subunit's domains III and IV. When the inactivation gate is closed, the flow of [tex]Na^+[/tex] through the channel is stopped. As a result, both the activation and inactivation gates must be open to enable sodium ions to enter the cell.
Hence , the correct option is (a).
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