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In Marker Analysis, how are STRs related to alleles? Be sure to define each term (STR and allele) and explain how the two result in different band patterns when run in gel electrophroresis.

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Answer:

The system of DNA profiling used today is based on PCR and uses simple sequences or short tandem repeats (STR). ... These STR loci (locations on a chromosome) are targeted with sequence-specific primers and amplified using PCR. The DNA fragments that result are then separated and detected using electrophoresis.

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