Rationalists (like Descartes) and empiricists (like Locke and Berkeley) differ on their epistemology approach because:

A. rationalists affirm we can never make mistakes when we appeal to the senses

B. both rationalists and empiricists doubt that there is anything that can be known with certainty;
C. rationalists say that reasoning is based on sense experience; empiricists say that sense experience is based on reasoning.
D. empiricists say that reasoning is based on sense experience; rationalists say that sense experience is based on reasoning.