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1. Thiamin deficiency was observed only in the Chinese community even though all three communities had the same staple (rice) diet. 2. Explain. On packages of enriched rice sold in supermarkets, the rice preparation directions state that the rice should not be washed before cooking. Explain. 3. Severe metabolic acidosis caused by high levels of lactate is often associated with thiamin deficiency. Explain.4. Provide two plausible explanations for what might cause above normal levels of pyruvate in blood and urine. How can one determine which of the two explanations is correct? 5. Why does thiamin utilization increase among cancer patients? 6. A negative correlation exists between the need for thiamin and the amount of fat in the diet. Explain.

Sagot :

Answer and Explanation:

1. This is likely to happen because Chinese people often wash rice before cooking. This act ends up reducing the amount of thiamine that rice has. This causes the Chinese to consume rice that is low in thiamine, which causes the deficiency of this nutrient in the Chinese population.

2. The recommendation that rice should not be washed before cooking is precisely to avoid the loss of thiamine, since thiamine is a water-soluble protein, so when we wash rice, this vitamin is dissolved before being consumed.

3. Thiamine deficiency stimulates the accumulation of lactic acid and pyruvate in the body. This causes muscle damage, which can lead to lactic acidosis, as thiamine is essential in lactic acid metabolism.

4. Abnormal levels of pyruvate can be caused by a deficiency of thiamine in the body, or by eating foods that cause the creation of pyruvate in the body. We can determine which explanation is correct, through a blood test that will be able to determine the amount of thiamine in an organism.

5. Thiamine is directly related to the proliferation of cancer cells. The more thiamine is used, the greater the proliferation of cancer cells, that is, low levels of thiamine accelerate cancer.

6. Thiamine requirement is inversely proportional to the amount of fat in the diet, as increased thiamine can lead to increased appetite and increased fat accumulation.

It has been established that cancerous cells utilize a lot of thiamin. This is why there is often low thiamin levels in cancer patients.

Thiamin deficiency also called beri - beri results when an individual does not have enough vitamin B in the body. It is common in Chinese communities because they wash rice thereby reducing the thiamine in rice.

The recommendation that rice should not be washed is on order not to loose the thiamin content of the rice.

When there is not enough thiamin  in the body, it can lead to the presence of excess of lactic acid and pyruvate in the body.

There can be excess pyruvate in the body when there is a deficiency of thiamin   or when we consume foods that contain excess pyruvate.

It has been established that cancerous cells utilize a lot of thiamin. This is why there is often low thiamin levels in cancer patients.

When the level of thiamin in the body increases, the appetite of the individual increases and fat increases also.

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