The correct answer to this open question is the following.
Although you forgot to attach the options for this question, we can say the following.
In a well-known study of California men, being aggressive and impatient was found to be related to heart disease, which shows that psychological factors are considered to be important in the development of disease.
Some psychological studies have confirmed that Type "A" personalities tend to develop or better said, are more prone to develop heart diseases due to stress. These kinds of individuals work in stressful mode, they are considered to be very competitive and get angry easily. They usually work all day and part of the night, so their level of stress is very high.