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A person with blood group A produces antibodies against B. A person with blood group B produces antibodies against A. A person with blood group AB produces no antibodies. How can you explain this?

Sagot :

A person with blood group A produces antibodies against B. A person with blood group B produces antibodies against A. A person with blood group AB produces no antibodies can be explained by: A and B alleles are co-dominant. Therefore, both A and B carbohydrates are present on the cell. 

It should be based on the principles of immunology to understand this phenomenon: the immune system produces antibodies against an antigen that it does not possess

The AB group contains the A and B antigens on the red blood cells, so it can not produce anti-A antibodies or anti-B antibodies since it already possesses antigen A and B (otherwise it will develop autoimmunity).