We have 3⁴ = 81, so we can factorize this as a difference of squares twice:
[tex]x^8 - \dfrac1{81} = \left(x^2\right)^4 - \left(\dfrac13\right)^4 \\\\ x^8 - \dfrac1{81} = \left(\left(x^2\right)^2 - \left(\dfrac13\right)^2\right) \left(\left(x^2\right)^2 + \left(\dfrac13\right)^2\right) \\\\ x^8 - \dfrac1{81} = \left(x^2 - \dfrac13\right) \left(x^2 + \dfrac13\right) \left(\left(x^2\right)^2 + \left(\dfrac13\right)^2\right) \\\\ x^8 - \dfrac1{81} = \left(x^2 - \dfrac13\right) \left(x^2 + \dfrac13\right) \left(x^4 + \dfrac19\right)[/tex]
Depending on the precise definition of "completely" in this context, you can go a bit further and factorize [tex]x^2-\frac13[/tex] as yet another difference of squares:
[tex]x^2 - \dfrac13 = x^2 - \left(\dfrac1{\sqrt3}\right)^2 = \left(x-\dfrac1{\sqrt3}\right)\left(x+\dfrac1{\sqrt3}\right)[/tex]
And if you're working over the field of complex numbers, you can go even further. For instance,
[tex]x^4 + \dfrac19 = \left(x^2\right)^2 - \left(i\dfrac13\right)^2 = \left(x^2 - i\dfrac13\right) \left(x^2 + i\dfrac13\right)[/tex]
But I think you'd be fine stopping at the first result,
[tex]x^8 - \dfrac1{81} = \boxed{\left(x^2 - \dfrac13\right) \left(x^2 + \dfrac13\right) \left(x^4 + \dfrac19\right)}[/tex]
