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Why do the polypeptides made in prokaryotes always contain formyl methionine as the first amino acid?
The terminator tRNA adds formyl methionine first.
The terminator tRNA adds methionine amino acid first.
The initiator tRNA adds formyl methionine first.
The initiator tRNA adds methionine amino acid first.

Sagot :

zhamauriwright12

Answer:

The initiator tRNA adds formyl methionine first.

Explanation:

i just took the quiz and it was right :)

The initiator tRNA adds formyl methionine first in translation process.

what is Translation?

It is the formation of protein from m-RNA.

Protein synthesis can be separated into three steps, similar to mRNA synthesis: Initiation, Elongation, and Termination.

The creation of an initiating complex is the first step in protein synthesis.

  • The short 30S ribosome, the mRNA template, three initiation factors (IFs; IF-1, IF-2, and IF-3), and a specific initiator tRNA called tRNA Metf are all part of this complex in E. coli.
  • Met-tRNAi is a specific tRNA that carries methionine and serves as the initiator tRNA.
  • The eukaryotic initiation complex identifies the 5′ cap of the eukaryotic mRNA instead of the Shine-Dalgarno sequence, then tracks down the mRNA in the 5′ to 3′ direction until the AUG start codon is recognized.
  • The 60S subunit interacts to the Met-tRNAi, mRNA, and 40S subunit complex at this moment. After that, the initiator tRNA binds with the AUG start codon (or rarely, GUG).
  • The amino acid methionine is carried by this tRNA and is formylated once it is attached to the tRNA. Between the formyl carboxyl group and the amino group of the methionine, a fake peptide link is formed. The initiation factor IF-2 is involved in the binding of the fMet-tRNA Metf.
  • Every polypeptide chain generated by E. coli starts with the fMet, but it is normally deleted after translation is completed. A typical Met-tRNA Met inserts a non-formylated methionine when an in-frame AUG is encountered during translation elongation.
  • The 30S ribosomal subunit is linked by the 50S subunit to create the translation complex once the initiation complex is formed. mRNA, the 40S small ribosomal subunit, eukaryotic IFs, and nucleoside triphosphates constitute a comparable initiation complex in eukaryotes (GTP and ATP).
  • The methionine on Met-tRNAi, the charged initiator tRNA, is not formylated. Met-tRNAi, on the other hand, differs from other Met-tRNAs in that it can bind IFs.

so, the correct answer is option c.

To know more about translation in prokaryotes here

https://brainly.com/question/13621278

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