some genetic disorders decrease susceptibility to malaria. what is an example of a genetic disorder that has this effect?

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05-10-2021
Medicine

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some genetic disorders decrease susceptibility to malaria. what is an example of a genetic disorder that has this effect?

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ari4415 ari4415 · Answer 1 · 2021-10-06T11:11:02-04:00

ari4415 ari4415

06-10-2021

Perhaps related to the high frequency of diseases related to genes conferring resistance to malaria is that many of resistance variants, such as G6PD deficiency, the thalassaemias, sickle-cell anaemia, and ovalocytosis, are “loss of function” mutants and lead to reduced expression or altered gene product.

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