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The cAMP receptor protein (CRP) is said to be responsible for positive regulation of the lac operon because ________.

Sagot :

CRP bound to the CRP-binding site stimulates the transcription of the lac operon

The cAMP receptor protein (CRP) is responsible for the positive regulation of the lac operon because CRP binds to a specific DNA sequence close to the lac promoter, causing increased transcription.

The repressive effect of glucose is effected through a protein called catabolite activating protein (CRP) and cAMP.

  • The catabolite activating protein (CRP) is a dimer that, when it binds to cAMP, activates and stimulates the transcription of the lactose operon genes.

  • The activator protein CRP-cAMP is necessary for the binding of RNA polymerase to the promoter of the lactose operon genes.

Therefore, we can conclude that cAMP and its receptor protein and its binding to the promoter of the lac operon, causes a DNA twist that facilitates the binding of RNA polymerase to the promoter.

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