Okazaki fragments are fragments that are derived as a result of the replication process in the DNA to form the lagging strand.
There is a need to produce okazaki fragment on the lagging strand because the template for the lagging strand runs from the 5' to the 3' direction. And production should be in the 5' to 3' direction.
- As okazaki fragments are short sequences of DNA nucleotides which are synthesized discontinuously and later joined by enzyme DNA ligase to create the lagging strand during DNA replication.
- This lagging strand is produced in pieces/fragments because the DNA polymerase can only synthesize in the 5′ to 3′ direction.
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