A combination of acid and amine with similar molecular masses would be used.
When two substances capable of diffusing are placed at extreme ends of a sealed tube, each will diffuse towards the opposite end of the tube.
If the 2 substances are capable of reacting to form a white ring like in the case of the acid and the amine, the point at which the white ring will form would depend on the rate of diffusion of each substance.
According to Graham's law of diffusion, the rate of diffusion of substances is inversely proportional to the square root of their molecular masses. Going by this law, gases with similar molecular weight will have similar rates of diffusion.
Thus, 2 substances (gases) with similar molecular masses, left to diffuse in the opposing ends of a sealed tube will diffuse to meet around the halfway point between the two ends of the tube where they can react and form a white ring.
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