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Explain why AlCl3 must be kept dry (free of water) and the glassware should be dry when performing Friedel-Crafts alkylation. Incorporate relevant chemical reaction(s) to support your answer.

Sagot :

Friedel-Crafts alkylation requires dry conditions because AlCl3 may combine with water thereby hindering the reaction.

Friedel-Crafts involves the introduction of an alkyl group into a benzene ring. This occurs by electrophilic substitution of a proton on the aromatic ring with an alkyl group.

The set up must be free from water because water could inactivate the Lewis acid (AlCl3) due to combination of the Lewis acid with water thereby hindering the reaction.

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