Agonists activate the receptor thereby increasing activity at the synapse while antagonists generally prevent agonists from activating the receptors thereby decreasing activity at the synapse.
- An agonist is the component that has the ability to increase the activity carried out by another substance.
- The agonists work from their faculty of coupling to a cell-type receptor, in this way, they manage to generate a certain action in the cell.
- The antagonists are the compounds that cause the opposite when they bind to the receptor, they cause a blockade by decreasing the activation of a synaptic receptor.
Therefore, we can conclude that agonists are compounds capable of increasing the action of synapse and blockers (antagonists) decrease activity at the synapse.
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