The dorsal/ventral pattern is initially established in drosophila development by the gradient of a transcription factor called dorsal protein.
Dorsal proteins are synthesized after fertilization, when dorsal is translated, it forms a complex with a protein known as cactus in the cytoplasm.
The dorsal/ventral axis in the Drosophila is determined by morphogenesis which is established by 12 maternal effect genes along with the dorsal and cactus.
Therefore, the dorsal/ventral pattern is initially established in drosophila development by the gradient of a transcription factor called dorsal protein.
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