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Sagot :
In E. coli if RNA polymerase is missing the sigma factor, then transcription initiation would not occur at the appropriate initiation sites.
What is a sigma factor?
Transcription is a process in which a copy of the DNA is made in the form of mRNA. The sigma factor is a very important molecule that is required for the proper functioning of the transcription process. E. coli, which is a prokaryote, needs the sigma factor to allow the RNA polymerase to bind to the DNA molecule to start the transcription process. Once the sigma factor binds to the RNA polymerase molecule, it can recognize the promoter region of the transcription unit and starts reading the DNA strand to synthesize the mRNA strand.
Learn more about the sigma factor here:
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