Cholecystokinin, which is produced in the small intestine, inhibits gastric secretions in the stomach. True or false?.

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01-08-2022
Medicine

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Cholecystokinin, which is produced in the small intestine, inhibits gastric secretions in the stomach. True or false?.

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tutorconsortium202 tutorconsortium202 · Answer 1 · 2022-08-08T13:04:05-04:00

True, Cholecystokinin(CCK), which is produced in the small intestine, inhibits gastric secretions in the stomach.

What is Cholecystokinin?

Cholecystokinin is a peptide hormone of the gastrointestinal system responsible for stimulating the digestion of fat and protein.
Cholecystokinin, officially called pancreozymin, is synthesized and secreted by enteroendocrine cells in the duodenum, the first segment of the small intestine.
Its presence causes the release of digestive enzymes and bile from the pancreas and gallbladder, respectively, and also acts as a hunger suppressant.
CCK is synthesized and released by enteroendocrine cells in the mucosal lining of the small intestine (mostly in the duodenum and jejunum), called I cells, neurons of the enteric nervous system, and neurons in the brain. It is released rapidly into the circulation in response to a meal.
The greatest stimulator of CCK release is the presence of fatty acids and/or certain in the amino acids in the chyme entering the duodenum.
In addition, release of CCK is stimulated by monitor peptide (released by pancreatic acinar cells), CCK-releasing protein (via paracrine signalling mediated by enterocytes in the gastric and intestinal mucosa), and acetylcholine (released by the parasympathetic nerve fibers of the vagus nerve).
Once in the circulatory system, CCK has a relatively short half-life.

To learn more about Cholecystokinin: https://brainly.com/question/15451892

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