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Chemiosmotic coupling holds true to explain the synthesis of atp by energy released from electron transport chain.
Peter Mitchell suggested that it would be possible to produce ATP by using an electrochemical gradient of protons across a membrane. The process is known as chemiosmosis because he compared it to osmosis, which is the diffusion of water across a membrane. Only a membrane protein known as ATP synthase allows hydrogen ions in the matrix space to pass through the inner mitochondrial membrane.
ADP is converted into ATP by ATP synthase as protons pass through. Oxidative phosphorylation describes the process by which ATP is produced in mitochondria by chemiosmosis. Proton gradient, ATP synthase, and proton pump are the essential elements required for the chemiosmosis process.
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