The four layers of the digestive tract from superficial to deep are the mucosa (adjacent to the lumen), submucosa, muscularis externa, and serosa.
The innermost tunic of the wall is known as the mucosa or mucous membrane layer. The digestive tract's lumen is lined with it. The mucosa is made up of epithelium, a layer of lamina propria, a loose layer of connective tissue, and the muscularis mucosa, a thin layer of smooth muscle. The mucosa in some areas produces folds that enhance its surface area. The mucosa's specific cells secrete hormones, digestive enzymes, and mucus. Other glands' ducts travel to the lumen through the mucosa.
The mucosa is surrounded by a substantial layer of loose connective tissue known as the submucosa. Blood arteries, lymphatic vessels, and neurons are also present in this stratum. This layer might contain glands.
An inner circular layer and an outside longitudinal layer make up the two layers of the smooth muscle that moves the digestive tract. The two muscle layers are separated by the myenteric plexus.
The adventitia is a connective tissue that makes up the digestive tract's outermost layer above the diaphragm. It is referred to as serosa below the diaphragm.
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