Fructose-1, 6-bisphosphatase is activated in response to a glucagon signal.
What is the purpose of Glucagon signals?
- Glucagon signals specify that fuel molecules are required in the bloodstream.
- So these signals activate Fructose-1, 6-bisphosphatase (F1, 6BP) so as to increase the level of sugar and other fuels required for production of energy.
- In the process of gluconeogenesis, new glucose molecules are synthesized from other non carbohydrate sources.
- As glucose is required in the bloodstream so F-1, 6BP should be activated as it acts as a rate limiting enzyme in gluconeogenesis.
- Gluconeogenesis occurs when the dietary intake of glucose is very low.
- Glucose is required as a source of energy by almost all body cells so in case of less oxygen it is synthesized from other molecules like amino acids.
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