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Sagot :
The arrangement of subunits in the pdh (pyruvate dehydrogenase) complex ensures that in the inner mitochondrial membrane.
- By turning pyruvate into acetyl-coenzyme A, the pyruvate dehydrogenase complex (PDHc) connects glycolysis to the citric acid cycle.
- The pyruvate dehydrogenase complex (PDHc), consists of the three enzymatically active subunits pyruvate dehydrogenase, dihydrolipoyl transacetylase, and dihydrolipoyl dehydrogenase, which links the citric acid cycle and subsequent oxidative phosphorylation to the pathways for glycolysis, gluconeogenesis, and lipid and amino acid metabolism. E1 is a part of PDH and catalyzes pyruvate's oxidative decarboxylation. Dyhydrolipoyl transacetylase, also known as E2, catalyzes the addition of an acetyl group to coenzyme A to produce acetyl CoA.
- The oxidative decarboxylation of pyruvate, a -keto acid, by the pyruvate dehydrogenase complex produces carbon dioxide (CO2) and the acetyl group of acetyl-coenzyme A or acetyl-CoA with the release of two electrons, carried by NAD, in five successive processes.
- Learn more about pyruvate dehydrogenase here brainly.com/question/16346028
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