For every one NADH molecule oxidized at complex I, 10 HYDROGEN IONS are pumped across all of the complexes from the mitochondrial matrix to the inner membrane space
Cellular respiration has three main stages: glycolysis, the Krebs cycle, and oxidative phosphorylation.
What is Oxidative phosphorylation ?
During oxidative phosphorylation, the reduced form of nicotinamide adenine dinucleotide (NADH) helps to carry electrons from one reaction to another across a series of molecular complexes.
- The electron transport chain of oxidative phosphorylation is coupled to the generation of an electrochemical proton (H+) gradient across the mitochondrial inner membrane.
- Subsequently, this proton H+ gradient is then used to produce ATP by an ATP synthetase.
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