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During the loading of tbp, what event displaces the binding of tafs 11 and 13 from one of the stirrups of tbp?

Sagot :

The DNA kink of 80˚ is induced by tight binding of TBP which ultimately displaces the binding of TAFs 11 and 13.

What is TBP associated factor?

The protein which bind to  TATA-binding protein during the initiation transcription is called as TAFs are the component of TFIID multimeric protein complex which is a transcription initiation factor .

The key component of  transcription initiation machinery,  and play a role in core promoter recognition, assembly of the pre-initiation complex

These have  a signature domain named N-terminal histone-like fold domain (HFD).

Hence, DNA kink of 80˚ is induced by tight binding of TBP

Learn more about Transcription factor, here:

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