inducible intestine-specific deletion of krüppel-like factor 5 is characterized by a regenerative response in adult mouse colon

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02-09-2022
Biology

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inducible intestine-specific deletion of krüppel-like factor 5 is characterized by a regenerative response in adult mouse colon

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kjuli1766 kjuli1766 · Answer 1 · 2022-09-06T06:28:50-04:00

Krüppel-like issue five (KLF5) is a member of a zinc-finger (ZF)-containing transcription component circle of relatives including 20 members that play vital roles in various organic tactics.

Like component 5 (KLF5) is a member of a zinc-finger (ZF)-containing transcription element circle of relatives consisting of 20 participants that play important roles in numerous organic methods.

The Kruppel-like elements (KLFs) belong to a family of zinc finger-containing transcription elements that alter diverse cellular strategies, inclusive of development, differentiation, proliferation, and apoptosis.

Abstract Krüppel-like element 5 (KLF5) is a seasoned-proliferative transcription factor this is expressed in dividing epithelial cells of the intestinal crypt. Leucine-wealthy repeat-containing G-protein coupled receptor five (Lgr5) has been recognized as a stem cell marker in each small intestinal and colonic epithelial cell.

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