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delayed parkinson's disease diagnosis amoung african americans: the role of reporting of disability. neuroepidemiology

Sagot :

African-Americans may have delayed diagnosis of Parkinson's disease (PD), which could explain racial variations in the observed prevalence of the condition. In order to understand if perception of disability explains racial inequalities, we compared the stages at which African-American and white PD patients presented for medical attention.

Explanation:

Parkinson's disease:

Movement is impacted by Parkinson's disease, a degenerative nervous system condition. The first signs may be a barely perceptible tremor in just one hand at first. Although the disorder frequently results in tremors, it also frequently slows or stiffens movement.

What is the Parkinson disease neuroepidemiology?

The prevalence of Parkinson disease (PD) is a widespread neurological illness that progresses over time and manifests both motor and non-motor symptoms. A fresh etiologic theory for PD may be offered by the neuroepidemiology of the condition. However, there are substantial issues with the epidemiologic study of PD.

Methods

We used the Philadelphia Veterans Affairs Medical Center's records of veterans who had just been diagnosed with PD to calculate differences in reporting symptoms as the difference in part 2 (disability) and part 3 (symptoms) z-scores on the Unified Parkinson Disease Rating Scale (motor impairment). Predictors of stage at diagnosis were found using ordinal logistic regression.

Results:

Veterans with a mean age of 70.1 years were found, including 16 black veterans (n = 16) and 58 white veterans (n = 58). African-Americans were more likely to underreport disability in relation to motor impairment (81 vs. 40%, p 0.01) and appeared at a later Hoehn + Yahr stage than whites (median Hoehn + Yahr stage 2.5 vs. 2.0, p = 0.02). The influence of race on stage of diagnosis was mostly explained by under-reporting of impairment, according to multivariate analysis.

Conclusions:

African-Americans may underreport their disabilities, which could explain why they receive PD diagnoses at later stages than white people. In this study, the reasons behind racial differences in PD are partially explained.

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