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gold ja, rimal b, nolan a, et al. a strategy of escalating doses of benzodiazepines and phenobarbital administration reduces the need for mechanical ventilation in delirium tremens. crit care med. 2007 mar;35(3): 724-30.

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ICU patients admitted to the facility. Guidelines that place a strong emphasis on rising bolus doses of diazepam, along with barbiturates when appropriate, greatly decreased the requirement for mechanical ventilation and showed signs of trending toward shorter ICU stays and fewer nosocomial infections.

What is nosocomial infection?

Nosocomial infections, also known as healthcare-associated infections (HAI), are an infection or illnesses that develop while undergoing medical treatment but were absent at the time of admission.

Which five nosocomial illnesses are most common?

Staphylococcus aureus, Pseudomonas aeruginosa, and E. coli are the bacteria that cause nosocomial infections most frequently, according to the CDC. Urinary tract infections, lung pneumonia, surgical site infections, bacteraemia, gastrointestinal, and skin infections are a few of the prevalent nosocomial diseases.

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Patients who experience acute alcohol withdrawal and delirium tremens frequently develop resistance to benzodiazepines at regular dosages.

What does the study imply?

  • According to case studies, these patients frequently require acute care, and many of them also need mechanical ventilation. However, there are limited data available regarding the methods of treatment and results for these patients in the medical intensive care unit (ICU).
  • A substantial percentage of patients who are brought to a medical ICU specifically for treatment of severe alcohol withdrawal need mechanical ventilation.
  • Guidelines that place a strong emphasis on rising bolus doses of diazepam, along with barbiturates when appropriate, greatly decreased the requirement for mechanical ventilation and showed signs of trending toward shorter ICU stays and fewer nosocomial infections.

Learn more about the benzodiazepines with the help of the given link:

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