The medieval development that was a direct contributing factor to the spread of disease is A. Renewed urbanization
What is urbanization?
Urbanization is the process of more people moving into urban areas. Urbanization, which results in an increase in the number of the urban population and the extent of urban areas, is mostly caused by individuals moving from rural to urban areas.
When historians looked into how the plague spread, they found that fleas, which are frequently seen on rodents like rats and mice, were the disease's primary carrier. As a result, it is now known that the rats that carried the plague traveled in caravans and on merchant ships, which is how the disease spread.
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