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chloride shift
The exchange of chloride ions for bicarbonate through tissue capillaries is called the chloride shift.
What transpires when a chloride shift occurs?
- Chloride shift is a process that takes place in the human body as oxygen and carbon dioxide are transported through the blood.
- RBCs absorb carbon dioxide, which is then converted to H2CO3 by the enzyme carbonic anhydrase.
- H2CO3 then breaks down into bicarbonate ions and hydrogen ions.
Where in the human body does chloride shift occur?
- The process of bicarbonate (HCO3) and chloride (Cl) being exchanged across the membrane of red blood cells is known as chloride shift, sometimes referred to as the Hamburger phenomena or lineas phenomenon and named after Hartog Jakob Hamburger (RBCs).
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