It is true that most cells are relatively small for reasons related to the of substances into and out of cells
All cells, whether prokaryotic or eukaryotic, must be tiny. Consider the volume and size of a typical cell. Not all cells are spherical, although most are. The formula for a sphere's surface area is 4πr2, whereas the formula for its volume is 4πr3/3. As a cell's radius grows, its surface area grows as the square of its radius, while its volume grows as the cube of its radius (much more rapidly).
As a result, as a cell grows larger, its surface area-to-volume ratio drops. The same idea would apply if the cell were shaped like a cube (below). If the cell becomes too big, the plasma membrane will not have enough surface area to sustain the increased diffusion rate. In other words, when a cell develops, its efficiency decreases. Divide to become more efficient; create organelles that conduct specialized jobs to become more efficient.
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