Answered

Westonci.ca connects you with experts who provide insightful answers to your questions. Join us today and start learning! Get immediate answers to your questions from a wide network of experienced professionals on our Q&A platform. Discover in-depth answers to your questions from a wide network of professionals on our user-friendly Q&A platform.

Activated g protein-coupled receptors can? a. bind gtp b. open an ion channel c. raise cytosolic calcium d. a and b are correct e. a, b and c are correct

Sagot :

bharathparasad577

The correct statements are:

A bind GTP

B open an ion channel and

C raise cytosolic calcium

  • The majority of cellular responses to environmental inputs are mediated by G protein-coupled receptors (GPCRs).
  • Upon ligand activation of the receptor, it binds to heterotrimeric G protein partners, facilitates the exchange of GTP to GDP, cleaves the G protein into subunits, and mediates downstream signaling.
  • Arrestins also enable GPCRs to activate multiple signaling pathways. Small modifications at the ligand-binding or orthosteric sites are amplified to produce larger conformational changes, translocating the GPCR to its active state.
  • Structures, spectroscopic data, and computer simulations of various GPCRs crystallized in active and inactive states provide molecular knowledge of allosteric coupling between ligand binding and G-protein or arrestin interactions. Instead of being adjusted, the connection is loose.

Therefore, option e. is correct.

Learn more about GPCR:

https://brainly.com/question/13186034

#SPJ4

Thank you for choosing our platform. We're dedicated to providing the best answers for all your questions. Visit us again. Thank you for your visit. We're dedicated to helping you find the information you need, whenever you need it. Discover more at Westonci.ca. Return for the latest expert answers and updates on various topics.