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Ras Homework
Wild type
cells without
growth factor
Wild type
cells with
growth factor
Mutations that
keep Ras in
the GTP-
bound form
Mutations that
keep Ras in
the GDP-
bound form
Mutations that
inactivate
GAP
Mutations that
overexpress
RTK
Receptor
Tyrosine
Kinase
Off
On
due April 23, 2019
Ras
GDP-bound
GTP-bound
Name
ERK
Inactive,
Not
phosphorylated
Active,
Phosphorylated
Cell
Proliferation
No
proliferation
Proliferation


Ras Homework Wild Type Cells Without Growth Factor Wild Type Cells With Growth Factor Mutations That Keep Ras In The GTP Bound Form Mutations That Keep Ras In T class=