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A patient receives a 125-mg injection of medicine every 6 hours. The table shows the amount of medicine in the bloodstream, m(t), after t hours. For which hour is the rate of change of medicine in the bloodstream expected to be the largest, based on the data?

t, hours 0 6 12 18 24
m(t), milligrams 125 188 219 235 243
Group of answer choices

1 hour

8 hours

15 hours

19 hours