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tRNA knows where to deliver the amino acid in the growing amino acid chain as the amino acid is delivered to the correct codon on the mRNA by the tRNA, which matches its anticodon to the appropriate codon.
In a particular order, tRNAs deliver amino acids to the mRNA. An attraction between an anticodon, a complementary triplet of nucleotides on the tRNA, and a codon, a three-nucleotide sequence on the mRNA, determines the order in which these three elements occur. Along with identifying the specific amino acid that the tRNA carries, this anticodon also specifies it.
A covalent bond holds amino acids to the ribose of the terminal adenosine and the sequence CCA at the 3' end of every tRNA. At the opposite end of the folded tRNA, the anticodon loop, which binds by complementary base pairing, then recognizes the mRNA template.
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