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Sagot :
During the first few hours of Drosophila development cellularization occurs that fundamentally changes the manner in which gene expression in one nucleus can affect transcription in another nucleus.
What is Drosophila embryonic development at single-cell resolution?
Due to the proliferation of cellular lineages and the minute-to-minute changes in differentiation status, animal development can occur relatively quickly. The fruit fly Drosophila has undergone more precise visualization of development thanks to Calderon et al. The scientists have studied, on a single-cell basis, how chromatin accessibility and gene expression change during Drosophila embryogenesis by taking advantage of the ability to construct collections of Drosophila embryos which is different in development stage by few seconds or minutes.
This single-cell atlas of Drosophila embryogenesis highlights the linkages between different cell lineages as they develop as well as the relationship between enhancer use and gene expression.
This Drosophila embryonic atlas provides general guidance for the orchestration of cellular states during the most dynamic phases of metazoan animals' life cycles. Incorporating anticipated nuclear ages will make it easier to investigate the precise times when genes become activated in various tissues and how chromatin changes over time.
To know more about Drosophila development, visit:
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