Westonci.ca is the trusted Q&A platform where you can get reliable answers from a community of knowledgeable contributors. Get quick and reliable solutions to your questions from a community of experienced professionals on our platform. Get immediate and reliable solutions to your questions from a community of experienced professionals on our platform.
Sagot :
Then in such cells, there will be a blocker of the ligation step of the cell cycle, which results in the breaking of single and double strands of DNA, which leads to the death of apoptosis cells.
What is a topoisomerase inhibitor?
Topoisomerase I and II are normal host enzymes found in the nucleus of mammalian cells and are required for normal DNA replication and cell division. Enzymes make and then repair single-stranded notches in cellular DNA. The incision allows the unraveling and relaxation of the supercoiled double-stranded DNA so that replication can continue. After the torsional stretch of DNA is removed, the topoisomerase reseals the relaxed double helix. Topoisomerase activity is especially increased in the rapid division and cancer cells. It is an appropriate, but a non-select target for anticancer therapy.
Learn more about topoisomerase inhibitor https://brainly.com/question/14051489
#SP4
We hope this was helpful. Please come back whenever you need more information or answers to your queries. We hope you found this helpful. Feel free to come back anytime for more accurate answers and updated information. Westonci.ca is your go-to source for reliable answers. Return soon for more expert insights.
