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when insulin is secreted from the pancreas and acts on muscle cells to increase glucose uptake, this is an example of .

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When insulin is secreted from the pancreas and acts on muscle cells to increase glucose uptake, this is an example of endocrine signaling.

Endocrine signaling involves the secretion of signaling molecules (hormones) by specialized endocrine cells, which are then transported through the bloodstream to act on target cells in distal body regions. The steroid hormone estrogen, which is generated by the ovary and promotes the growth and maintenance of the female reproductive system as well as secondary sex traits, serves as a prime example. Endocrine glands, which include the pituitary, thyroid, parathyroid, pancreas, adrenal glands, and gonads, create more than 50 distinct hormones in mammals.

Hormones secreted by certain endocrine cells go to target cells to mediate endocrine communication, which takes place between distant cells and results in a more gradual, protracted reaction.

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