Two types of mutations in the gene encoding phosphoribosylpyrophosphate synthetase, or prs, have been observed. one mutation alters the regulatory site on the enzyme, whereas the other mutation alters the promoter of the enzyme. both mutations result in increased prs activity. how will the two different mutations in prs affect the transition between the r and t states of the enzyme? the mutation in the regulatory site will not affect the transition between the r and t states. the mutation in the promoter