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Sagot :
An artificial version of the human hormone parathyroid hormone, which is found in teriparatide injection (PTH). It functions by encouraging the body to produce new bone while boosting bone strength and density.
Teriparatide was superior to bisphosphonates in avoiding fracture in postmenopausal women with osteoporosis in both the short- and long-term follow-up periods, according to the findings of our meta-analysis. Teriparatide prevented both vertebral & non-vertebral fractures better than bisphosphonates. PTH increases the production of pro-osteoclastogenic cytokines such receptor activator of nuclear factor kappa ligand (RANKL) and macrophage colonists factor in osteoblasts and osteocytes to exercise its catabolic effects. Osteoporosis for postmenopausal women hormone who are high risk of bone fracture is treated with teriparatide injection. It lessens the chance that postmenopausal women with osteoporosis may have a bone or spine fracture.
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