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Sagot :
Nitric oxide and prostanoids generated by nearby endothelium and macula densa cells both help to increase renin release.
What causes the blood pressure to rise when renin is secreted?
Renin itself has no effect on blood pressure. Instead, it does this in conjunction with aldosterone and angiotensin. Aldosterone causes your blood vessels to constrict, and angiotensin causes your kidneys to retain water and salt. This causes your body to retain more fluid, which in turn raises your blood pressure.
Renin's main purpose is therefore to eventually raise blood pressure, which then helps to restore the kidneys' perfusion pressure. Juxtaglomerular kidney cells that are sensitive to variations in renal perfusion pressure secrete renin through stretch receptors in the vascular walls.
learn more about renal system refer
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