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Sagot :
Phagocytes ingest and destroy the pathogen through a process called phagocytosis.
Pathogens are recognized by phagocytes, which then phagocytose and eliminate them. Recognition is often accomplished through the use of phagocyte receptors that bind to molecules commonly present on pathogens, called pathogen-associated molecular patterns (PAMPs). Chemicals from the pathogen or dead damaged abnormal cells act as attractants causing phagocytes to move towards the pathogen. Phagocytes have several receptors in their cell surface membrane that recognize and attach to chemicals on the surface of the pathogen. They create a vesicle known as a phagosome by engulfing the pathogen. Particles commonly engulfed by white blood cells include bacteria, dead tissue cells, protozoa, various dust particles, pigments, and other tiny foreign bodies. Encapsulated bacteria are more difficult to ingest. In the absence of specific antibodies recognizing the bacteria, opsonization cannot occur and the bacteria repel the phagocytes.
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