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Histone proteins are used by the cell to package the large chromosome into the nucleus.
Histone proteins are the ones that wind the DNA around themselves in order to facilitate its packaging. Together they form a structure called nucleosome. There are 5 types of histone proteins: H1, H2A, H2B, H3 and H4. The H1 is not directly involved in packaging but it is the linker protein. The rest of the proteins also regulate the expression of the genetic material.
Chromosome is the highly compact form of DNA. It is this form of DNA that gets inherited by offspring from parents. The structure of chromosome consists of two sister chromatids joined together at the region called centromere.
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