Which of the following illustrates a benefit of cell-to-cell communication?

A.) Secondary messengers, including ionsitol triphosphate and Calcium Ions are relevant as a result of neurotransmitters being released into a cleft between neural cells and inhibitors.
B.) Plasmodestmata allow animal cells to present ligands to receptor mediated inhibitors p53-cancer mediated apoptotic response
C.) Cells contain antigens that might provoke killer t cells, dendritic cells, natural killer cells, and other cells associated with innate immune response
D.) Larger responses can be initiated in cell communication involving direct contact due to the ability of tyrosine kinase phosphorylation multiple proteins at once