When using negative pressure technique to reconstitute a powder, the diluent may be added by gently pressing on the plunger as long as you ___.

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05-12-2022
Medicine

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When using negative pressure technique to reconstitute a powder, the diluent may be added by gently pressing on the plunger as long as you ___.

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AyushiJain10 AyushiJain10 · Answer 1 · 2022-12-13T00:47:38-05:00

Use within 48 hours after reconstitution and store in the refrigerator. Use within 24 hours if maintained at room temperature.

What happens during reconstitution?

Reconstitution is the process of transforming a dried medication into a liquid before administration by combining it with a sterile diluent. The technologies used for reconstitution typically range from vial adaptors to vial-to-vial systems to sophisticated dual chamber reconstitution systems.

A syringe and transfer needle are often used to manually extract the diluent from one vial and transfer it to the vial containing the lyophilized product. The components are transferred, then blended until the mixture is thoroughly reconstituted. This procedure might occasionally take up to 30 minutes, and it demands the user's whole attention. Although patients and caregivers may also undertake the reconstitution procedure, a skilled healthcare expert usually does so.

There is a need for an easy and efficient method of reconstituting and administering lyophilized items by a user in a home environment given the general shift of therapy from the clinic to the home.

To learn more about reconstitution

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