Cyanide, oligomycin, and 2, 4-dinitrophenol (DNP) are inhibitors of mitochondrial aerobic phosphorylation. Which of the following statements correctly describes the mode of action of the three inhibitors? A) Cyanide and 2, 4-dinitrophenol inhibit the respiratory chain, and oligomycin inhibits the synthesis of ATP. B) Cyanide inhibits the respiratory chain, whereas oligomycin and 2, 4-dinitrophenol inhibit the synthesis of ATP. C) Cyanide, oligomycin & 2, 4-dinitrophenol compete with O_2 for cytochrome oxidase (Complex IV). D) Oligomycin & cyanide inhibit synthesis of ATP; 2, 4-dinitrophenol inhibits the respiratory chain. E) Oligomycin inhibits the respiratory chain, whereas cyanide and 2, 4-dinitrophenol prevent the synthesis of ATP.
