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Renal blood flow increases in the maternal urinary system during pregnancy.
A frequent and dangerous consequence of pregnancy is renal impairment. Understanding normal physiology during pregnancy helps put alterations in pregnancy that cause renal dysfunction into context and may offer hints for improved therapy.
The glomerular filtration rate (GFR) increases dramatically due to decreases in net glomerular oncotic pressure and increases in renal size as a result of hormonal changes that occur during pregnancy. These changes result in increased blood flow to the kidneys and impaired autoregulation. Through the three pregnant trimesters and into the postpartum period, the mechanisms for maintaining an elevated GFR shift. Important reasons of pregnancy-specific renal impairment have been further researched, but more has to be learnt.
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