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imagine a transmembrane molecule that lies in the plasma membrane and acts as a receptor for an extracellular signaling molecule. when the ligand-binding domain is inserted into the er during synthesis of this transmembrane molecule, will it lie on the lumen side of the er or the cytoplasm side?

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During the production of the transmembrane protein located in the plasma membrane, a ligand binding domain is introduced into the ER and is located on the lumen side of the ER.

Endoplasmic Reticulum is referred to as ER. It is a cell organelle that is exclusive to eukaryotic cells. Rough ER (RER) and Smooth ER are two different forms of ER (SER). The SER is engaged in the synthesis of lipids, whereas the RER is involved in the synthesis of proteins.

Each cell has an exterior membrane called a plasma membrane. Its job is to keep the cells' interiors isolated from their surroundings. Additionally, it functions as a semi-permeable barrier to control traffic passing through it.

For more details regarding eukaryotic cells, visit:

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