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Signaling at a synapse events: Action potential arrives at axon terminal, Voltage-gated calcium channels open, Neurotransmitter released into synaptic cleft ,Neurotransmitter binds to receptors,Graded potential generated in postsynaptic cell and Neurotransmitter is removed from the synaptic cleft
Similar to paracrine signaling, synaptic signaling is separated from it by a unique structure called a synapse in the cell that is sending and receiving the signal. Only cells with synapse connections can communicate synaptically, such as a neuron and the muscle under the influence of brain activity. A chemical neurotransmitter is released by neuron A as a result of an action potential at the connection (synapse) between the two neurons. Neuron B's ability to fire its own action potential might be aided (excited) or hampered (inhibited) by the neurotransmitter.
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